Without knowing your game or seeing your swing, the best advice I can give you is if you're left handed - get a left hand driver, and if you're right handed - get a right hand driver.
Seriously, there are too many variables between what we play and what you play. All Titleist drivers are top of the line, but designed to fit different swings. The specific model is just the start. The shaft choice is what will fit you more than the model.